(815) 732-2499 Serenity Hospice & Home 1658 S. Illinois Route 2 Oregon, IL 61061 Driving Directions. Administrative Staff and Community Nursing Phone: (815) 732-2499 Toll-free: (888) 421-3100 Fax: (815) 732-6077. Palliative Care Phone: (815) 881-1800. Office Hours for Serenity Hospice & Home: 8:00 am to 4:30 pm Monday thru Friday Nurses are on-call 24/7/365