What is hothotspot therapeutics? HotSpot Therapeutics is a developer of a therapy platform designed to discover medicines and provide proper treatment. The company's platform helps to identify hotspots and locate pathway treatments for cancer, metabolic and rare diseases, leverages a database of hotspot structures, harnessing the power of data science in its multidisciplinaryWho is the co founder of hotspot? Prior to co-founding HotSpot, Jonathan served as Chief Business Officer at Nimbus Therapeutics, where he helped establish the company’s drug discovery platform and pipeline.How is hotspot different to conventional drug discovery? Unlike conventional drug discovery, which focuses on targeting the active sites of proteins, HotSpot has developed a technology platform to uncover nature’s privileged regulatory hotspots – pockets remote from the active site that are critical to protein function.What is a regulatory hotspot in molecular biology? Hotspots allow chemists to exploit a range of new molecular scaffolds or chemotypes. Traditional drug discovery aims to shut down a protein's catalytic site. Nature uses regulatory hotspots to control proteins precisely. A flexible protein 'tail' ...
View Joe Wahle's business profile as Vice President & Head of Immunology at HotSpot Therapeutics. Find contact's direct phone ...
HotSpot Therapeutics to Present New Data Indicating Successful Targeting of CBL-B at 2021 Society for Immunotherapy of Cancer Annual Meeting. Boston, Mass., Nov. 9, 2021 — HotSpot Therapeutics, Inc., a biotechnology company pioneering the discovery and development of first-in-class allosteric [...]